Blade Runner 2099 Trailer Reveals Replicant Rule and a Cure Quest
Prime Video's new trailer introduces Michelle Yeoh and Hunter Schafer's intertwined fugitives, with the limited series due November 25 and a search for a replicant cure at its centre.
By Hushread Stories, written with AI from 9 outlets · First published 11 Oct 2026
In brief
- Prime Video unveiled a new Blade Runner 2099 trailer at New York Comic Con on October 10.
- The limited series takes place in a reborn Los Angeles, fifty years after Blade Runner 2049.
- Michelle Yeoh plays a dying replicant whose life becomes intertwined with Hunter Schafer's undercover human.
- The story involves a search for a cure for all replicants in a world they now control.
- The eight episode limited series is scheduled to arrive on Prime Video on November 25.
Timeline · 5 moments
November 25 Prime Video release date reported
Bleeding Cool ↗Convention coverage details the team's detective story framing
The Hollywood Reporter ↗Search for a cure emerges as central plot
Screen Rant ↗Trailer reveals replicant rule and continuing struggles with mortality
/Film ↗Prime Video premieres new trailer at New York Comic Con
Variety Movies ↗How it started
"Blade Runner 2099" moves the story forward by half a century. According to Variety Movies, the Prime Video limited series is set 50 years after "Blade Runner 2049", in a reborn Los Angeles.
Its central pairing brings together Michelle Yeoh and Hunter Schafer as fugitives. Variety Movies identifies Schafer's character as Cora, while The Hollywood Reporter describes the pair as a dying replicant and an undercover human whose lives become intertwined.
How it unfolded
On October 10, Prime Video premiered the new trailer at New York Comic Con, according to Variety Movies. Gizmodo Tech described it as the series' first full-length trailer, teasing the aftermath of a replicant uprising.
The footage establishes a changed balance of power. /Film reported on October 10 that replicants have conquered the world but still struggle with identity and mortality. Their dominance has not resolved the question of how long they can live.
The search for a cure gives that problem a concrete place in the plot. Screen Rant highlighted the quest for a "cure for all replicants" on October 10. Deadline Hollywood reported the following day that Schafer's character teams up with Yeoh's replicant to find it.
Coverage published on October 11 also added the team's account of the series. The Hollywood Reporter reported that the cast, showrunner and executive producers discussed a detective story set when replicants take over. Forbes reported that Yeoh and Schafer attended the Saturday convention event to discuss the series and unveil the trailer.
Where it stands
The series is scheduled to arrive on Prime Video on November 25, according to Bleeding Cool. Deadline Hollywood describes it as an eight-episode limited series and reports that Prime Video released key art alongside the trailer.
The preview now gives viewers a clearer premise: replicants hold power, one of them is dying, and an undercover human becomes part of the search for a cure. The detective-story framing reported by The Hollywood Reporter adds another element to that pursuit.
What to watch
The next scheduled milestone is the November 25 premiere reported by Bleeding Cool. The central unresolved questions are how Cora and Yeoh's replicant come together, and whether the cure they seek can be found. The supplied coverage establishes the quest, not its outcome.


